Hemolytic anemia caused by chemicals and toxinsAnemia - hemolytic - caused by chemicals or toxins
Hemolytic anemia caused by chemicals and toxins is a lack of red blood cells that occurs when red blood cells are excessively damaged by certain chemicals or toxins.
Possible substances that can cause hemolytic anemia include:
- Anti-malaria drugs (quinine compounds)
- Intravenous water infusion (not half-normal saline or normal saline)
- Metals (chromium/chromates, platinum salts, nickel compounds, copper, lead, cis-platinum)
- Phenazopyridine (Pyridium)
- Rho immune globulin (WinRho)
- Snake bites (some snake venom contains hemolytic toxins)
This list is not all-inclusive.
Mentzer WC, Schrier ML. Extrinsic nonimmune hemolytic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 47.
Michel M. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 160.